The Best Supplements To Reduce Estrogen Dominance

 by Dr. Steve Hruby, D.C.
Reviewed by Dr. Steve Hruby, D.C.

SuperHumans are the toughest, fittest, healthiest and happiest human beings on this planet. My mission is to help you realize your superhuman potential and learn how to live a long, happy and healthy life.

  Fact Checked
 by Rhealyn Tropia, RMT
Reviewed by Rhealyn Tropia, RMT

I’m a content organizer, fact-checker and super mom who ensures content is medically-reviewed, highly accurate, and engaging. My passion is organizing information and ensuring the facts are presented in a manner that is interesting and easy to understand.

supplements to reduce estrogen dominance

Are you feeling tired, anxious, and moody? You may be experiencing the effects of estrogen dominance. This condition occurs when too much estrogen is inside the body relative to progesterone.

While estrogen is an important hormone, too much of it can lead to some severe health problems; that’s why there are supplements to reduce estrogen dominance.

Did you know that estrogen dominance is a leading cause of infertility and weight gain in women? If you are looking for ways to reduce estrogen dominance, look no further.

This blog post will discuss the best supplements to help you get back on track. These supplements can help improve your overall health and reduce the effects of estrogen dominance.

What Is Estrogen Dominance?

This is a hormonal imbalance in both women and men. Estrogen dominance occurs when too much estrogen is inside the body relative to other hormones, like progesterone.

This can lead to various symptoms, including weight gain, mood swings, fatigue, and more.

Estrogen dominance can be caused by various factors, including exposure to environmental toxins, stress, and more. 

Estrogen dominance also has been linked to an increased risk of several conditions, including breast cancer, endometriosis, and uterine fibroids. Therefore, it is essential to seek treatment if you think you may be suffering from this condition.

Moreover, estrogen dominance can impact both sexes. It can lead to low libido, erectile dysfunction, and more in men. In women, it can cause irregular periods, PMS, and more. 

How to Lower Estrogen Levels With Supplements: Top 15 Supplements for Estrogen Dominance

Lowering estrogen levels is essential for many reasons, including reducing the risk of hormone-related cancers, improving fertility, and relieving symptoms of estrogen dominance.

As women age, their bodies produce less and less estrogen. This can lead to several problems, including hot flashes, night sweats, vaginal dryness, and weight gain. Estrogen dominance can also cause mood swings, anxiety, and depression.

different supplements

Several supplements can help reduce estrogen levels and alleviate the symptoms of estrogen dominance. Here are 15 of the best:

  • Calcium D-glucarate 
  • Vitamin B6 
  • Sulforaphane 
  • Probiotics
  • DIM (Diindolylmethane)
  • Omega-3 fatty acids 
  • Turmeric
  • Milk thistle 
  • Taurine
  • Magnesium
  • Selenium
  • Vitamin D3 
  • Zinc
  • Resveratrol 
  • N-Acetyl Cysteine

Calcium D-glucarate

Calcium D-glucarate is a compound found in fruits and vegetables, especially cruciferous vegetables such as broccoli and Brussels sprouts. It works by inhibiting an enzyme that allows estrogen to be reabsorbed into the body, thereby reducing its levels.

Studies have shown that calcium D-glucarate can reduce hot flashes, night sweats, and other menopausal symptoms in as little as two weeks. It can also help improve bone density and reduce the risk of breast cancer.

If you are looking for a natural way to reduce estrogen dominance, calcium D-glucarate is an excellent option. You can find it in supplement form at most health food stores.

Vitamin B6

Vitamin  B6  is a water-soluble vitamin that acts as a coenzyme in the metabolism of amino acids and aids in synthesizing nucleic acids, hemoglobin, and neurotransmitters. It’s involved in over 100 enzymatic reactions inside the body. 

Vitamin B-Complexes are great for helping to reduce estrogen dominance because they help to detox the liver. The liver is responsible for metabolizing and clearing excess estrogen from the body.

If the liver is not functioning optimally, estrogen can build up inside the body and lead to estrogen dominance. Vitamin B-Complexes help to support liver function and detoxification, which can help reduce estrogen dominance.

This estrogen control supplement is one of the best vitamins that lower estrogen. Like the vitamins that enhance the immune system, it is a water-soluble vitamin that helps the body in over 100 ways.

This makes it one of the most essential vitamins for women, especially those struggling with estrogen dominance.

Vitamin B-Complexes can be found in many foods, such as leafy greens, chicken, beef, fish, and eggs. You can also find them in supplement form.


Sulforaphane is an organic sulfur compound found in cruciferous vegetables like broccoli, cabbage, and Brussels sprouts. This supplement can help balance estrogen levels by inhibiting the aromatase enzyme, which converts testosterone into estrogen.

eating broccoli

Sulforaphane is also a potent natural supplement that can help reduce estrogen dominance.

You can find this supplement in cruciferous vegetables like broccoli, cabbage, and Brussels sprouts. It works by inhibiting the aromatase enzyme, which converts testosterone into estrogen.


Probiotics are live bacteria that are beneficial to gut health. They can be found in fermented foods like yogurt and sauerkraut or in supplement form. Probiotics help to increase the number of good bacteria in the gut, which can reduce inflammation and improve hormone balance.

Yogurt, sauerkraut, and other fermented foods are excellent sources of probiotics. You can also take probiotic supplements to ensure you get enough good bacteria. Probiotics can help improve gut health, reduce inflammation, and balance hormones.

Like the gut cleansing diet, or the gut-cleanse diet food plan, probiotics can be a helpful tool in reducing estrogen dominance. This is because they help to remove excess estrogen from the body and promote a healthy balance of hormones.

DIM (Diindolylmethane)

DIM is a compound found in cruciferous vegetables such as broccoli, cabbage, and kale. It works by helping the body to break down estrogen into weaker forms, making it less likely to cause problems. Supplementing with DIM can help reduce estrogen dominance symptoms, such as weight gain, PMS, and breast tenderness.

DIM is available in supplement form and can be taken in doses of 100-200mg per day. It is also possible to get DIM from eating cruciferous vegetables, though it would be challenging to eat enough to get the same effects as from a supplement.

If you are struggling with estrogen dominance, adding a DIM supplement to your menu could be a helpful way to reduce your symptoms.

Omega-3 Fatty Acids

Omega-3 fatty acids are a type of polyunsaturated fat that have numerous health benefits. One of these benefits is the ability to reduce estrogen dominance.

In a study, women who took omega-three supplements had significantly lower levels of estradiol (a form of estrogen) than those who did not.

You can find omega-3 fatty acids in fish, like mackerel, salmon, and sardines. You can also find them in flaxseeds, hemp, and chia seeds.

Omega-3 Fatty Acids

You can also take omega-three supplements in the form of capsules or liquids. Omega-3 fatty acids are an excellent option to reduce estrogen dominance.


Turmeric is a popular spice used in Indian cuisine. It has also been used for centuries as a medicinal herb.

Turmeric contains curcumin, a powerful antioxidant that can help protect the body against damage from free radicals. Curcumin also has anti-inflammatory properties, which can be beneficial for arthritis and joint pain.

Turmeric supplements are available in many forms, including capsules, tablets, and powders. It is essential to choose a supplement with a high percentage of curcuminoids, as this is the active ingredient in turmeric. Look for a supplement that contains at least 95% curcuminoids.

One study found that taking a turmeric supplement (500 mg per day) for eight weeks reduced joint pain and stiffness in people with arthritis.

Another study found that taking a curcumin supplement (600 mg per day) for eight weeks reduced inflammation and improved symptoms of osteoarthritis.

If you are considering taking a turmeric supplement, talk to your healthcare provider, as it can interact with certain medications.

Milk Thistle 

Milk thistle is a plant used for centuries as an herbal remedy for various ailments. The active ingredient in milk thistle is silymarin, which is thought to have liver-protecting properties. Some studies have shown that milk thistle can help reduce estrogen levels in women with PCOS (polycystic ovary syndrome).

Thorne’s Milk Thistle Extract is a high-quality supplement that contains 80% silymarin. Milk thistle may be worth trying if you’re looking for a natural way to reduce estrogen dominance.


Taurine is an amino acid in many foods, including meat and fish. It’s also available as a supplement. Taurine has many bodily functions, including acting as an antioxidant and helping regulate electrolyte balance.

Some research suggests that taurine may help to reduce estrogen levels. One study found that taurine supplementation decreased rat estrogen levels.

While more research is needed, taurine may be a promising supplement for reducing estrogen levels. If you’re interested in trying it, taurine supplements are available online.


Magnesium is one of the best supplements you can take to reduce estrogen dominance. Magnesium helps to regulate hormones and has a calming effect on the body, which can help reduce anxiety and stress.

It also helps to improve sleep quality. Magnesium can be found in leafy green vegetables, nuts, and seeds. You can also take a magnesium supplement.

leafy green food

Magnesium can also help to reduce water retention. Water retention can cause bloating and weight gain. Magnesium helps to expel water from the body and can also help to reduce bloating.

Magnesium is an excellent supplement for overall health, but it is especially beneficial for reducing estrogen dominance. If you struggle with estrogen dominance, consider adding magnesium to your menu or taking a magnesium supplement.


Selenium is a micronutrient that is essential for good health. It functions as an antioxidant, scavenging harmful toxins from the body. Selenium also helps to regulate the thyroid gland and is necessary for proper immune system function.

Many foods contain selenium, but supplementation is the best way to ensure you get enough. The recommended daily dose of selenium is 200 micrograms.

One of the best supplements for reducing estrogen dominance is selenium. This micronutrient scavenges harmful toxins from the body, helps to regulate the thyroid gland, and is necessary for proper immune system function.

Vitamin D3

We all know that vitamin D is essential for strong bones, but did you know it can also help regulate estrogen levels?

Vitamin D works by binding to receptors inside the body and helping control enzyme production. One study found that women who took a vitamin D supplement had lower levels of estradiol, the main form of estrogen, than those who did not.

You may consider taking a supplement if you don’t get enough vitamin D from the sun or your diet. The recommended dose is 600-800 IU per day. You can also get your vitamin D levels checked by a doctor to see if you need to take a higher dose.

Vitamin D3 is the best form of vitamin D to take, and you can find it in many different supplements.


Zinc is an essential mineral that plays a role in over 300 different enzyme reactions inside the body. It’s involved in DNA synthesis, cell growth, wound healing, and immune function (to name a few).

Zinc is also critical for fertility and reproductive health. Unfortunately, many people are deficient in this vital nutrient.

Studies show that zinc deficiency can lead to an increase in estrogen levels. Supplementing with zinc can help correct this imbalance and reduce estrogen dominance.

Zinc is found in food sources like oysters, beef, chicken, pumpkin seeds, and lentils. You can also find it in supplement form. The recommended daily dosage is 11-13 mg for adult women.


Resveratrol is a powerful antioxidant found in the skin of red grapes, peanuts, and some berries. Resveratrol works by inhibiting an enzyme called aromatase, which is responsible for converting testosterone into estrogen. In one study, resveratrol decreased aromatase activity by up to 70%.

berries in a bowl

In addition to its effects on estrogen, resveratrol has also been shown to improve blood sugar control and increase insulin sensitivity. It’s also been shown to reduce inflammation and improve heart health.

All these effects make resveratrol an excellent choice for those looking to reduce estrogen dominance.

N-Acetyl Cysteine

N-Acetyl Cysteine (NAC) is an amino acid and one of the best supplements to reduce estrogen dominance. NAC has anti-estrogenic effects and can help detoxify the body of excess estrogen. It is also a powerful antioxidant that helps to protect the body from free radical damage. 

N-Acetyl Cysteine is a safe and effective supplement that both men and women can take. It is essential to consult with a healthcare practitioner before taking any supplement, especially if you have a medical condition.

What Causes Estrogen Dominance?

Various factors can contribute to estrogen dominance. One of the most common is an imbalance in the progesterone ratio to estrogen. This can be due to several reasons, including:

  • Progesterone levels may naturally decline as we age
  • We may have a deficiency in certain nutrients that are necessary for the production of progesterone
  • We may be exposed to environmental toxins that can disrupt the balance of hormones in our body

Another common cause of estrogen dominance is “leaky gut syndrome.” This is when the lining of our intestines becomes damaged, allowing toxins and undigested food particles to enter our bloodstream. This can lead to inflammation and an imbalance of hormones.

There are a few lifestyle factors that can contribute to estrogen dominance as well. These include:

  • Having chronic stress
  • Being overweight or obese
  • Exposure to environmental toxins
  • Eating a diet high in processed foods and sugar

High Estrogen Symptoms

Elevated estrogen levels can wreak havoc on your health, causing several unwanted symptoms.

The most common high estrogen symptoms include:

  • Weight gain, particularly around the hips and thighs: Estrogen affects where fat is stored inside the body.
  • Fatigue: High estrogen can cause fatigue and make it difficult to concentrate.
  • Headaches: Estrogen dominance is a common trigger for headaches and migraines.
  • Bloating: Estrogen can cause bloating and water retention.
  • Breast tenderness: High estrogen levels can cause breast tenderness and enlargement.
  • Irregular periods: High levels of etrogen can cause irregular, heavy, or missed periods.
  • Mood swings: Many women with high estrogen report feeling irritable, anxious, or depressed.

These symptoms can be highly disruptive to your life, making it difficult to concentrate at work or enjoy your hobbies. They can also negatively impact your relationships.

If you’re experiencing any of these symptoms, you must see your doctor to rule out other potential causes. This way, you can be sure that your symptoms are due to high estrogen levels.

How to Treat Estrogen Dominance Naturally

There are a few different ways that you can treat estrogen domination naturally.

One of the best things you can do is to ensure you get enough nutrients for hormone balance. This includes zinc, magnesium, vitamin B complex, and omega-3 fatty acids.

You should also make sure to avoid any foods or environmental toxins that can contribute to estrogen dominance. This includes processed foods, soy products, and pesticides.

In addition to the supplements discussed above, a few other supplements can help treat this condition. These include:

  • I-three-C (Indole-three-carbinol): This is another compound found in cruciferous vegetables that helps to break down estrogen inside the body.
  • Vitex (Chasteberry): This herb helps balance hormones and regulate the menstrual cycle.
  • Cinnamon: This spice has been shown to help regulate insulin levels, impacting hormone balance.
  • Protein: Getting enough protein is essential for proper hormone function.

These supplements can be taken in pill form or added to your menu through foods like broccoli, cabbage, and Brussels sprouts.

Making lifestyle changes is also essential for treating estrogen dominance. This includes losing weight if you’re overweight, reducing stress levels, and getting regular exercise.

Following these steps can help reduce high levels of estrogen symptoms and restore hormone balance.

You must see your doctor if you suspect you are suffering from estrogen dominance. They can order tests to confirm your diagnosis and help you develop a treatment plan.

Don’t let estrogen dominance control your life. With the proper treatment, you can feel like yourself again.

Foods to Avoid Estrogen Dominance

Certain foods can contribute to estrogen dominance. These include:

  • Dairy products: Dairy can contain traces of growth hormones and other hormones that can disrupt the endocrine system.
  • Soy products: Soy contains phytoestrogens, a type of estrogen in plants.
  • Refined carbohydrates: Refined carbs can cause insulin resistance, leading to estrogen dominance.
  • Alcohol: Alcohol consumption can increase the levels of estrogen inside the body.
  • Caffeine: Caffeine can contribute to anxiety and stress, which can disrupt hormone balance.

To avoid estrogen dominance, limiting your intake of these foods is essential. Instead, focus on eating whole, unprocessed foods rich in nutrients.

Foods That Lower Estrogen in Females

It’s no secret that estrogen dominance is a problem for many women today. But did you know that certain foods can help lower estrogen levels inside the body? Here are some of the best:

  • Cruciferous vegetables like broccoli, Brussels sprouts, and cabbage contain compounds that help to break down estrogen inside the body.
  • Flaxseeds are high in lignans, which are plant compounds that bind to estrogen receptors and help to remove them from the body.
  • Soy contains isoflavones, which have been shown to reduce estrogen levels in some studies. However, you should consume soy in moderation due to its potential goitrogenic effects.
  • Berries are high in antioxidants, which can help protect the body from the harmful effects of estrogen.
  • Green tea is rich in catechins, which have been shown to reduce estrogen levels inside the body.

Including these foods in your diet can help lower estrogen levels and reduce the risk of estrogen dominance.

Reducing Estrogen Levels: What Works?  (FAQs)

What Supplement Reduces Estrogen Levels?

Zinc, magnesium, and Vitamin B6 are the best supplements to reduce estrogen levels. These three minerals work together to block the conversion of testosterone to estrogen.

How Can I Lower My Estrogen Levels Quickly?

You can lower your estrogen levels quickly by following a low-estrogen diet. This means avoiding foods that contain estrogen or that promote estrogen production inside the body.

What Supplement Is Best for Estrogen Dominance?

The best supplement for estrogen dominance is Vitamin B6. Vitamin B helps to regulate estrogen levels inside the body and can help reduce the symptoms of estrogen dominance.


If you’re suffering from estrogen dominance, you can do several things to help reduce your symptoms. Making dietary and lifestyle changes is essential, and certain supplements can also be helpful.

The Infinity NAD + Longevity can also assist you in overcoming estrogen dominance by strengthening your immune system and protecting your cells from harm. Our NAD Longevity product aids in the reversal of the aging process. Forget about getting old; become Superhumn. Order Infinity NAD + Longevity today!

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