ProstaGenix Review: Ingredients, Side Effects, Pros and Cons

 by Dr. Steve Hruby, D.C.
Reviewed by Dr. Steve Hruby, D.C.

SuperHumans are the toughest, fittest, healthiest and happiest human beings on this planet. My mission is to help you realize your superhuman potential and learn how to live a long, happy and healthy life.

  Fact Checked
 by Rhealyn Tropia, RMT
Reviewed by Rhealyn Tropia, RMT

I’m a content organizer, fact-checker and super mom who ensures content is medically-reviewed, highly accurate, and engaging. My passion is organizing information and ensuring the facts are presented in a manner that is interesting and easy to understand.

prostagenix side effects

Thousands of men are looking for a prostate supplement to help them with their prostate problems. ProstaGenix is one of the most popular supplements on the market, and there are many different opinions about whether it works.

Suppose you are a man starting to experience problems with your prostate and wondering what some of the vitamins for immune system are; in that case, you may be interested in ProstaGenix.

This prostate supplement is said to improve men’s health, urinary flow, urgency, sleep patterns, and sexual arousal. ProstaGenix is known to be among the top-rated prostate supplements currently in the market, with support from the late Larry King. 

Before you decide whether or not to take ProstaGenix, let’s look at the ingredients in the supplement and the side effects you may experience while taking it. We will also discuss whether or not ProstaGenix is worth your money!

Prostate Health in Aging Men

As men age, they are most likely to have prostate problems. It is important to note not all prostate problems are cancer-related. 

The prostate is a gland in front of the rectum just below the bladder. It is responsible for producing the white fluid, which is combined with sperms from the testicles and other liquid to form semen. 

Prostate muscles are also responsible for ensuring semen is forcefully passed through the urethra during ejaculation. An interesting fact about the prostate is that it increases in size as men age.  

In younger men, the prostate is the size of a walnut. A study conducted from November 2009 to June 2010 revealed that the prostate volume doubled in size in each 10-year age group.

The volume increased from 5.5ml for participants between the age of 40-49 years to 1.1ml for subjects between the ages of 70-80 years. This is almost double the volume! 

When the prostate enlarges, it can cause urinary issues. For example, a person may start experiencing frequent urination, urinary tract infection, incomplete bladder emptying, etc. 

One common condition is prostatitis as a result of an infected prostate. When prostatitis becomes chronic, it causes recurring infection. However, this can be successfully treated with the long-term use of antibiotics. 

Another common condition is benign prostatic hyperplasia (BPH). It can cause urinary discomfort, reduced urinary flow, and increased risks of kidney issues. BPH can stimulate the production of prostate-specific antigen (PSA), which can indicate prostate cancer. 

Such conditions threaten an individual’s life and raise the need for treatment and non-invasive solutions such as prostate supplements. 

What are Prostate Supplements? 

Prostate Supplements have been on the market for quite a while. These supplements can neither cure nor treat prostate-related issues. They work by reducing symptoms of prostate-related problems such as frequent urination and painful ejaculation. Prostate supplements generally work by reducing prostate inflammation. 

Prostate supplements are the to-go-to solution when you are looking for a non-invasive fix or you just don’t prefer not taking too much medication. Some men who suffer from BPH report having success after using supplements. 

Despite the positive reviews surrounding prostate supplements, the evidence surrounding their effectiveness is not as strong.

Since doctors do not closely regulate supplements, safety, quality, and side effects may vary from one person to another. Before taking any prostate supplement, it’s best to consult with your doctor. 

What Is ProstaGenix and How Does It Work?

ProstaGenix is a prostate supplement with over 1000 mg of ingredients that help to improve prostate health. 

The most effective formula on the market is made using components from ProstaGenix. Beta-Sitosterol, a name used in commerce to describe a combination of sitosterol, stigmasterol, and campesterol, is the key ingredient.

This is the most potent nutritional supplement for prostate health that has ever been discovered by research. It also works well in reducing triglycerides and cholesterol.

The prostate pill supplement is also all-natural and made with pomegranate, green tea extract, and grape seeds as ingredients. A sophisticated combination of 11 necessary vitamins and minerals, including Vitamin D3, iodine, selenium, and zinc, is also included in the mix.

ProstaGenix gained traction after the late Larry King endorsed it. Larry King recommended the prostate to any man experiencing BPH and other prostate issues. Raining praise on the supplement, Larry King said that he has never felt more comfortable since he started using ProstaGenix.  

old man sitting on the coach

Its main ingredient functions by inhibiting the accumulation of more cholesterol in the prostate and breaking down the already accumulated fats. It also helps regulate the general body’s cholesterol. 

Pros Of ProstaGenix

  • It has a 90-day money-back guarantee if it does not work for you.
  • They have superb customer service with a number you can call directly.
  • Since ProstaGenix is made from natural ingredients, there are few to no side effects while still showing signs of improving BPH symptoms.
  • You experience better sleep at night due to less urination.

Cons Of ProstaGenix

  • ProstaGenix does not have an official third-party testing lab
  • It is above the average market price compared to other prostate supplements.
  • Many components found in ProstaGenix lack supporting evidence of how they help prostate health.

Does ProstaGenix Really Work? 

Based on the available evidence, it seems likely that ProstaGenix can help improve urinary flow and reduce BPH symptoms.

Many satisfied customers have seen positive results from taking this supplement. However, it is important to note that this supplement has not been tested in a large-scale clinical trial.

As with any prostate supplements, results will vary from person to person. Therefore, it is possible that some men may not experience any benefit from taking ProstaGenix. If you are considering trying this supplement, be sure to talk to your doctor first.

The Benefits of ProtaGenix

ProstaGenix offers the most health benefits compared to any other prostate supplement on the market. If you were wondering how to strengthen your immune system, think no further.

man giving thumbs up

ProstaGenix benefits are added due to the all-natural ingredients in its composition. Below are some of the immediate benefits that are attributed to the use of ProtaGenix:

  • Reduced nightly urination, so no waking up during the night.
  • A complete bladder emptying
  • Higher libido and better sexual performance
  • Reduces urgency; therefore, no packing about wetting your pants
  • A stronger urine stream
  • Reduced toilet visits during the day

ProstaGenix also happens to have some long-term health benefits, which include:

  • Lower body cholesterol: ProstaGenix has ingredients that effectively lower bad cholesterol levels. However, it does not increase the level of good cholesterol levels.
  • Improves the heart’s health: Due to the low cholesterol levels, there is a low risk of heart disease.
  • It also helps people who have inherited high cholesterol tendencies from their families. It does this by reducing the low-density and total lipoproteins. ProstaGenix helps restart your immune system by breaking and reducing the bad cholesterol. 

ProstaGenix Ingredients Evaluation

Each ProstaGenix capsule contains eight minerals, vitamins, and two blends: one blend contains sterol, and the other contains polyphenols.

Let’s first concentrate on sterols, which are plant-based fats that ProstaGenix claims have the most significant effect on easing your symptoms associated with prostate issues, even though each ingredient may have health benefits.

The sterols available in ProstaGenix are:

  • Beta-sitosterol
  • Stigmasterol
  • Brassicasterol
  • Campesterol


Beta-sitosterol is highlighted as the main active ingredient in ProstaGenix, which is completed by a polyphenol blend and a combination of 11 vitamins and minerals.

Each serving contains 852mg of beta-sitosterol. It improves the symptoms of an enlarged prostate and lower body cholesterol. It reduces inflammation by limiting the amount of cholesterol that may penetrate the body and attach to the prostate.

Although there is no evidence to suggest that beta-sitosterol shrinks the prostate, it does appear to improve the symptoms of an enlarged prostate. Additionally, the efficacy doesn’t appear to increase when added to other compounds.

In earlier studies, beta-sitosterol was also shown to be an efficient treatment for BPH. The extensive research that has been done over the years has shown that beta-sitosterol helps treat the symptoms of BPH.

300mg Target Polyphenol Synergistic Blend

This blend is made up of three components which are:

  • Extract of Grapeseed
  • Quercetin
  • Pomegranate Seed Extract (gotten from pomegranate seeds)

The effectiveness of this blend in ProstaGenix is unknown, but the research conducted on animals in laboratories has shown some proof of their efficacy against prostate problems. Several researchers claim that Quercetin has anti-cancer qualities which may help prevent prostate cancer.

Pomegranate extract is a rich source of antioxidants. It has been demonstrated to inhibit prostate cancer cell growth and induce cell death in vitro. Still, in a significant placebo-controlled investigation, it had no appreciable effect on the course of prostate cancer.

pomegranate seeds

Grape-derived chemicals possess numerous anti-cancer substances, including those for prostate cancer. Additionally, in vivo anti-cancer activity of grape seed extract against specific prostate sickness has been seen in animal models. Even with the above information, it is still believed that more research is needed on the efficiency of grape extracts in curing cancers.

Vitamin D3, 400 IU

There are conflicting findings on vitamin D’s role in prostate health, particularly prostate cancer. A 2013 study suggests that vitamin D may positively impact BPH and prostate volume, with adequate vitamin D intake contributing to the reduction of enlarged prostates. However, more research is needed.

A study on mice found that animals with low vitamin D levels developed prostate cancer more frequently in their bones, highlighting the need to get enough of this mineral for prostate health.

A 2019 meta-analysis found that high-dose vitamin D supplements did not appear helpful for males with prostate cancer.

A 2020 study found no association between prostate cancer and blood vitamin D levels. However, men with vitamin D deficiency may be at higher mortality risk.

Lack of vitamin D has been associated with a higher risk of a number of other health issues, such as weak immunity and bone fractures, which are more common as individuals age. While there is conflicting information regarding prostate health, we advise you to take precautionary measures to keep your blood vitamin D levels within the usual range.

ProstaGenix consists of 400 IU of vitamin D3 per day or 100% of the RDA for men between 50-70.  According to the studies described above, this dosage is more of a preventative or maintenance dose than a high amount that could pose a risk.

Zinc, 15mg

Zinc is a mineral that contributes to healthy immunological performance (normal immune function). The human prostate contains a significant amount of zinc, yet the evidence for a connection between zinc and prostate cancer is conflicting.

According to a 2003 study, chronic zinc excess may be a factor in the emergence of prostate cancer. However, a more recent study raises the possibility that zinc transporters may contribute to the prevention of prostate tumors.

Furthermore, a 2009 review found evidence that zinc may play a preventive effect in prostate cancer, despite epidemiological studies producing conflicting results. While in a 2011 study, the researchers found that men with prostate cancer had a normal zinc status that was reduced by 83 percent, and men with BPH had a normal zinc status that was reduced by 61 percent, suggesting a link between zinc status and prostate health.

According to a more recent study, men over 50 who are zinc deficient are more likely to get BPH and prostate cancer, among other prostate health difficulties. ProstaGenix consists of 15 mg of zinc.

Selenium, 70 mcg

In a 2019 clinical experiment, selenium levels and prostate-specific antigen (PSA) were assessed before and after giving 481 males 200 mcg/day of selenium supplements for six months.

Researchers discovered that selenium supplementation had no effect on PSA levels and that selenium alterations were highly reliant on baseline selenium levels.


However, in younger, never-smoking men who took more zinc than the RDI and fewer vitamin B12 than the RDI, there was an inverse connection between PSA changes and selenium alterations. According to an additional study, even a mild selenium deficiency can increase the risk of prostate cancer.

For example, a 2011 Cochrane review discovered that males with the highest consumption of selenium had a 22 percent lower risk of prostate cancer than those with the most insufficient intake.

A potential inverse association between selenium levels and risk for prostate cancer was also discovered in an earlier 2003 meta-analysis that included 20 epidemiologic studies. Keep in mind that more selenium isn’t always better when it comes to health. Toxicity can result from taking too much selenium.

However, do not worry since ProstaGenix supplies all of the recommended daily allowances for selenium without exceeding.

Iodine, 150 Micrograms

We couldn’t find out much about how iodine helps improve prostate health. However, studies have shown that men with thyroid disease are at a higher risk of acquiring prostate disease. Nevertheless, the role of iodine in the prostate’s health remains speculative. 

Iodine supplementation has been shown to have anti-cancer benefits in several cancer types. However, a 2013 animal study found that it had no effect on stopping prostate cancer progression in their trial among mice.

Additional Ingredients in ProstaGenix

Apart from the ingredients mentioned above, ProstaGenix also consists of the following components:

  • Copper, two milligrams
  • Manganese, two milligrams
  • Chromium, 120 micrograms
  • Molybdenum, 75 micrograms

Although the ProstaGenix mix contains these trace elements, there is little proof of a connection between them and prostate health. In detailed research, manganese supplementation decreased the viability of prostate cancer cells; however, in other studies, chromium (VI) was found to accelerate prostate tumor growth. Patients with prostate cancer have been found to have increased blood levels of copper.

Scientific Evidence Associated With ProstaGenix

According to, two studies from the 1990s back up the claim that beta-sitosterol can enhance urine flow.

One of those trials showed that men with BPH who took 60 mg of beta-sitosterol daily achieved noticeable benefits, according to research published in The Lance in 1995.

clinical trial

The study concluded that “significant improvement in symptoms and urine flow metrics demonstrate the efficacy of beta-sitosterol in the treatment of benign prostatic hyperplasia.” The study also found that the prostate diameters in the beta-sitosterol-taking men did not decrease.

The study met the highest level of research by being randomized, placebo-controlled, and double-blind. It denotes that the study’s male participants did not know whether they were receiving beta-sitosterol or a placebo (fake tablet).

Men who consumed 130 mg of beta-sitosterol daily had better flow, less residual urine in their bladders, and overall more outstanding quality of life, according to a separate randomized, double-blind, placebo-controlled research.

These two studies were cited by the Linus Pauling Institute in their examination of the influence of beta-sitosterol on BPH urine symptoms. They moderated their conclusions even though they acknowledged that the research demonstrated success.

A review of four randomized studies published in 2000 found that beta-sitosterol reduces urinary symptoms in people with mild to moderate BPH safely and efficiently.

They said that beta-sitosterol might be particularly helpful for people who are more likely to experience adverse side effects and complications from the medicinal or surgical treatment of their BPH.

The last time this information was updated was in the 2000 study. Therefore research in 2012 gave an overview of BPH therapy using dietary supplements.

They confirmed the findings of the 2000 report, concluding that beta-sitosterol is safe and only causes “mild and uncommon side effects.”

Although a few clinical trials’ findings imply that relatively low doses of phytosterols help lessen BPH-related symptoms in the lower urinary tract, the website notes that more studies are required to confirm these results.

These findings provide us reason to believe that beta-sitosterol may help lessen BPH’s urinary symptoms. But keep in mind that the research that led to this result is few and, in the majority of cases, older than 20 years.

ProstaGenix Dosage and Warnings

According to the manufacturer, ProstaGenix daily dosage is a single capsule three times a day. You can take it at any time of the day while on an empty stomach. A container can last you a month since it has 90 capsules. 

On this dosage, you are expected to receive your first results during the first ten days of full dosage.

However, on a regular dosage, you will receive more consistent results after a period of three to four weeks.  It’s best to talk to speak with your doctor before taking the supplement if you have any concerns.

You might be wondering is ProstaGenix safe for use. We have learned that while on the recommended dosage, ProstaGenix is safe for use for six months. However, we are unsure if it is still safe to use it after the first six months.

The capsules are simple to consume and can be taken with food or on an empty stomach. The approach you take is not mentioned in such a way.

You may be able to avoid ProstaGenix side effects the best by sticking to the recommended dose. We can’t fully confirm that because the dosage is more extensive than what was utilized in the research.

Additionally, ProstaGenix may interact poorly with medications in your body if you take Pravachol or Zetia. 

ProstaGenix Potential Side Effects

When looking at what are the side effects of ProstaGenix, it is important to note that the supplement does not have any severe side effects since it is made from natural ingredients unless you are affected by one of the components of ProstaGenix. However, you might experience some mild side effects. 

man with headache

Beta-Sitosterol can cause mild nausea, indigestion, and headache. It is also important to note that men should not use beta-sitosterol with sitosterolemia.

Sitosterolemia is an inherited unlikely condition where the body stores beta-sitosterol and other related fats. ProstaGenix rarely contributes to erectile dysfunction. 

It would be best if you took ProstaGenix only as recommended to avoid unusual side effects.

You should talk to your physician before taking prostate supplements, especially if urinary problems are present. This is because more severe issues could cause prostate conditions.

Even though the manufacturers claim that ProstaGenix is tested for purity and quality, the product does not bear any official third-party testing lab. Without an official third-party testing lab, there is less credibility.

ProstaGenix did, however, have a prize for triumphing in a prostate testing contest run by the esteemed independent testing organization, which examined label claims to see if they corresponded with the product’s actual ingredients.

The product not only received very high marks for this but was also thought to be the best value for beta-sitosterol compared to the other products assessed.

Last but not least, considering that ProstaGenix already contains 100% of the RDA for some vitamins and minerals, I would encourage users to be aware of any additional sources of the micronutrients included in this product.

When obtained from supplements, taking additional sources of some nutrients may result in excessive intake, which can be harmful.

How Long Does ProstaGenix Take To Work?

ProstaGenix takes around ten days to work. That is when the first visible effects are felt. However, continued intake of ProstaGenix will give consistent results after 30-40 days.

Does ProstaGenix Reduce the Size of the Prostate?

ProstaGenix does not reduce the size of the prostate. However, it inhibits further growth of the prostate and breaks down the cholesterol in the prostate area. It also helps improve prostate signs and symptoms. 

What Is the Best Prostate Supplement for Men?

The best prostate supplement for men is ProstaGenix. ProstaGenix is made from natural ingredients which do not have serious side effects. It also takes effect after only a few days of intake. 


ProstaGenix is a prostate supplement that is claimed to provide numerous benefits for men, including improved urinary function, reduced frequency of nighttime urination, and increased sex drive. 

While there is no clinical evidence to support the claims made by the manufacturers of ProstaGenix, the ingredients in the supplement have been studied for their potential prostate-related benefits.

Although more research is needed to confirm does ProstaGenix really work, the ingredients in the supplement show promise for providing benefits for men with prostate-related issues.

Also, you can try Aura, the highest quality Hemp/CBD Oil you can find! Aura contains cannabidiol, a substance that helps reduce pain and discomfort associated with benign prostatic hyperplasia.

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