Is Losing Weight With Phentermine and Wellbutrin Combination Safe?

  Reviewed
 by Dr. Steve Hruby, D.C.
Reviewed by Dr. Steve Hruby, D.C.

SuperHumans are the toughest, fittest, healthiest and happiest human beings on this planet. My mission is to help you realize your superhuman potential and learn how to live a long, happy and healthy life.

  Fact Checked
 by Rhealyn Tropia, RMT
Reviewed by Rhealyn Tropia, RMT

I’m a content organizer, fact-checker and super mom who ensures content is medically-reviewed, highly accurate, and engaging. My passion is organizing information and ensuring the facts are presented in a manner that is interesting and easy to understand.

losing weight with phentermine and wellbutrin

Losing weight is a challenge for many people. It is one of the most common resolutions people tend to have. If you are looking for a way to lose weight safely and effectively, you may consider using phentermine and Wellbutrin.

Losing weight with phentermine and wellbutrin is a very effective way to lose weight. However, there are some risks associated with using this combination.

You should always speak to your doctor before starting any weight loss program, including the use of phentermine and Wellbutrin.

This article will discuss whether or not this is a safe weight loss strategy and some potential side effects of this combination.

What Is Wellbutrin?

Wellbutrin is a prescription medication used to treat depression. You can also use it to help people quit smoking.

Wellbutrin works by increasing levels of norepinephrine and dopamine in the brain. These are two chemicals that are responsible for mood and energy.

Wellbutrin is an antidepressant medication classified as a norepinephrine and dopamine reuptake inhibitor (NDRI). This means it increases the levels of these two chemicals in the brain by blocking their reabsorption.

Moreover, the FDA also approved it for treating seasonal affective disorder (SAD) and major depressive disorder (MDD) in adults.

Wellbutrin is available as an immediate-release tablet, extended-release tablet, and an orally disintegrating tablet.

The extended-release tablet is designed to release the medication slowly over time. This allows for a steady level of the drug in your body throughout the day.

The dosage for Wellbutrin depends on several factors, including:

  • The severity of the condition
  • How you respond to Wellbutrin
  • The medical condition being treated
  • Other medical conditions you may have

Wellbutrin is typically taken two or three times a day. If you are taking the extended-release tablet, you must take it simultaneously each day. If you miss a dose of Wellbutrin, take it as soon as possible.

If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses of Wellbutrin at the same time.

How Does Wellbutrin Help You Lose Weight?

Wellbutrin can help you lose weight by increasing the levels of norepinephrine and dopamine in your brain.

These two chemicals are responsible for mood and energy. You will feel more energetic when they are increased, which can lead to burning more calories.

medication on prescription bottle

In addition, Wellbutrin can also help to suppress your appetite. This can lead to eating less, which can also help you lose weight.

Wellbutrin should not be used as a weight-loss drug. It is an antidepressant medication that can help with weight loss as a side effect.

If you want to lose weight, other methods, such as diet and exercise, may be more effective. Many meals that promote good health and a healthy gut are crucial for losing weight.

However, if you are struggling to lose weight and are also dealing with depression, Wellbutrin may be a good option.

What Is Phentermine?

Phentermine is a prescription medication used for the short-term treatment of obesity. It is typically prescribed for people who are at least 20% overweight and have been unable to lose weight through diet and exercise alone.

Phentermine is an appetite suppressant that works by affecting the central nervous system. It suppresses your appetite by making you feel full. Phentermine is available as a tablet, extended-release capsule, and solution. The dosage for phentermine depends on several factors, including:

  • Your age
  • Your medical condition
  • How you respond to the medication

Phentermine is usually taken once a day, 30 minutes before breakfast. If you are taking the extended-release capsule, take it with or without food. If you are taking the solution, take it with or without food but make sure you drink a full glass of water with each dose.

Phentermine is usually only prescribed for a short period because it is a habit-forming drug. Do not take phentermine for longer than prescribed by your doctor.

Do not share this medication with another person, even if they have the same medical condition as you.

Phentermine can help you lose weight by decreasing your appetite. But you will still need to eat a healthy diet and exercise regularly to lose weight and keep it off.

Also, if you take too much phentermine, you may experience severe or life-threatening side effects.

What Is Stronger Than Phentermine?

There are a few medications that are stronger than phentermine. These include:

  • Phendimetrazine: This medication is similar to phentermine. It is a stimulant that suppresses appetite and increases energy.
  • Diethylpropion: This drug is also similar to phentermine.  Like phentermine, it is used short-term for weight loss.
  • Bupropion: This medication is an antidepressant. It is also used to help people quit smoking. Bupropion can cause weight loss, but it is not known precisely how it does this.
  • Topiramate: This medication is most commonly used to treat seizures. You can also use it to prevent migraines. Topiramate may cause weight loss by decreasing appetite.
  • Tricyclic antidepressants: These medications are used to treat depression. You can also use them to suppress appetite.
  • Monoamine oxidase inhibitors: These medications are used to treat depression. You can also use them to suppress appetite.
  • Phentermine: This medication is a stimulant that suppresses appetite and increases energy. It is used short-term for weight loss.
  • Lorcaserin: This medication is used long-term for weight loss. It affects serotonin receptors in the brain to help decrease appetite and food intake.
  • Orlistat: This medication is used long-term for weight loss. It works by preventing the body from absorbing fat from food.

These medications are typically only prescribed if you have not been able to lose weight with phentermine alone. They should only be used short-term and under the supervision of a healthcare provider.

Wellbutrin and Phentermine for Weight Loss

Wellbutrin and phentermine are two popular medications that are often prescribed for weight loss. They both have different mechanisms of action to achieve this objective.

Phentermine is an appetite suppressant that works by stimulating the sympathetic nervous system. This increases norepinephrine and dopamine levels in the brain, which leads to reduced hunger and cravings. Phentermine is a short-term medication and is usually only prescribed for a few weeks.

losing weight

Wellbutrin, on the other hand, is an antidepressant that works by inhibiting the reuptake of dopamine and norepinephrine.

This leads to increased levels of these neurotransmitters in the brain, which have been shown to help with weight loss. Wellbutrin is a long-term medication and can be taken for months or even years.

Moreover, Wellbutrin has also been shown to help with other weight-related issues such as binge eating and night eating syndrome. This makes it a more comprehensive treatment for weight loss.

Phentermine is also a controlled substance and can be abused. This is why it is only prescribed for a short period.

However, Wellbutrin is not a controlled substance and can be taken for long periods. Therefore, it is generally considered a safer weight loss option.

Losing weight with the phentermine and Wellbutrin combination is safe if done under medical supervision. These medications can have side effects, so you must be monitored by a physician while taking them.

How Much Weight Can You Lose on Wellbutrin?

The amount of weight you can lose on Wellbutrin will depend on a few factors, such as:

  • Your dosage: Higher doses of Wellbutrin have resulted in more weight loss.
  • How long you take it: Generally, the longer you take Wellbutrin, the more weight you’ll lose.
  • Whether or not you make any lifestyle changes: Making healthy changes to your diet and exercise routine will help increase the weight you lose.

That said, most people who take Wellbutrin do lose some weight. In one study, people who took Wellbutrin lost an average of about five pounds over six months.

And in another study, about one-third of people lost over five percent of their body weight after taking Wellbutrin for a year.

Losing weight is never easy, and there are no guarantees that you’ll lose weight even if you take Wellbutrin. But if you’re struggling to lose weight, Wellbutrin may be worth a try.

If you decide to take Wellbutrin to lose weight, you must speak with your doctor first. They can help you determine if it’s the proper medication for you and what dosage would be best. They can also monitor your progress and help you make any necessary lifestyle changes.

Generally, people who take Wellbutrin lose around five pounds in the first six weeks. But everyone is different, so some people may lose more or less weight than this.

Talk to your doctor if you don’t see any weight loss after the first few weeks. They may need to adjust your dosage or switch you to a different medication.

How Much Wellbutrin Should I Take To Lose Weight?

The recommended starting dose of Wellbutrin for weight loss is 150 mg daily. However, your healthcare provider may prescribe a different dosage based on your individual needs. If you are taking phentermine along with Wellbutrin, the recommended total daily dose of Wellbutrin should not exceed 300 mg.

However, the dosage of Wellbutrin for weight loss may increase to 450 mg daily if needed. If you are taking Wellbutrin alone, the maximum recommended dose is 400 mg daily.

The dosage depends on a few factors, such as your age, weight, other medical conditions you have, and other medications you are taking.

Your healthcare provider will start you on a low dose of Wellbutrin and gradually increase your dose over time to reach the recommended dosage for weight loss.

Like the effective gut cleansing for weight loss, losing weight with Wellbutrin may not be easy or quick.

If you are interested in losing weight with the help of Wellbutrin, talk to your healthcare provider to see if this medication is proper for you. They can determine the best dosage for your individual needs and ensure that you take it safely.

How to Take Phentermine and Wellbutrin

If your doctor prescribes phentermine and Wellbutrin for you, you must follow their instructions on taking the medication.

Phentermine is usually taken once a day, in the morning, with or without food. Wellbutrin is generally taken two or three times a day with meals.

drinking meds

You should avoid drinking alcohol while taking phentermine and Wellbutrin, as it can increase the risk of side effects.

If you miss a dose of phentermine or Wellbutrin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses of phentermine at the same time.

Wellbutrin and phentermine weight loss dosage is different for everyone. Your doctor will determine the best dosage based on your weight, medical history, and other factors.

For Wellbutrin, the dosages are as follows:

  • Immediate-release tablets: 100 mg twice a day
  • Extended-release tablets (Wellbutrin SR): 150 mg once a day in the morning
  • Extended-release tablets (Wellbutrin XL): 300 mg once a day in the morning

For phentermine, the dosages are as follows:

  • Oral capsule: 15 mg to 30 mg once a day
  • Extended-release oral capsule (Ionamin): 15 mg to 30 mg once a day, taken before breakfast or within one hour after breakfast.

These are only general guidelines. Your doctor will determine the best dosage for you based on your individual needs.

Common Side Effects

Even though Phentermine and Wellbutrin are both FDA-approved medications, some common side effects are associated with their use. Some side effects are mild and go away independently, while others may require medical attention.

Before starting a new medication, one must be aware of the potential side effects. That way, you can take steps to avoid them or treat them if they do occur.

Wellbutrin Side Effects

The most common side effects of Wellbutrin are headaches, nausea, vomiting, and constipation. These side effects usually go away after a few days or weeks of taking the medication. If they don’t go away or if they’re bothersome, talk to your doctor.

cant sleep

Other potential side effects of Wellbutrin include:

  • Anxiety
  • Agitation
  • Insomnia
  • Dry mouth
  • Weight loss or gain
  • Changes in taste

These side effects are usually mild and go away on their own. However, talk to your doctor if you experience any of these adverse effects.

They might be able to change your medication’s dosage or prescribe a different one.

Phentermine Side Effects

The most common side effects of phentermine are dry mouth, headaches, trouble sleeping, and increased heart rate. These side effects usually go away after a few days or weeks of taking the medication. If they don’t go away or if they’re bothersome, talk to your doctor.

Other potential side effects of phentermine include:

  • Anxiety
  • Diarrhea
  • Insomnia
  • Agitation
  • Dizziness
  • Constipation

These side effects are rare and usually go away after a few days or weeks. If you experience any of these side effects, talk to your doctor.

Phentermine may also cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Can Phentermine and Wellbutrin Be Taken Together?

Yes, phentermine and Wellbutrin can be taken together. Many people who are trying to lose weight use this combination of medications.

Phentermine is an appetite suppressant that helps people eat less. Wellbutrin is an antidepressant that helps people feel fuller longer and prevents cravings.

Together, these two medications can help people lose weight safely. Thorough research has been conducted on the safety of this combination, and it is generally considered safe for most people.

However, as with any medication, there are potential side effects. Talk to your doctor about the risks and benefits of taking phentermine and Wellbutrin together. They can help you decide if this combination is right for you.

If you and your doctor decide this combination is right for you, follow all instructions carefully. Take each medication as prescribed, and do not increase your dose without talking to your doctor first.

Losing weight can be difficult. But with the help of phentermine and Wellbutrin, you may be able to reach your weight loss goals.

How Phentermine and Wellbutrin Can Be Taken Together

Phentermine and Wellbutrin can be taken together by mouth, usually two or three times a day. The phentermine dose is generally lower in the morning and higher in the evening, while the Wellbutrin dose is typically constant throughout the day.

It’s crucial to take each medication as prescribed and not to change your dose without talking to your doctor first. Taking too much of either drug can cause serious side effects.

woman drinking pills

You may take phentermine and Wellbutrin with or without food. If you experience stomach upset when taking either medication on an empty stomach, try taking it with food.

You should also take phentermine and Wellbutrin at least six hours apart, as taking them too close together can cause increased side effects.

Like a natural probiotic daily cleanse, you can take phentermine and Wellbutrin together to help you lose weight safely. Phentermine and Wellbutrin are both generally well-tolerated medications.

Phentermine & Wellbutrin Precautions

Before starting this weight loss journey, you must be aware of the phentermine and Wellbutrin precautions.

  • First and foremost, you should only use this combination if you are obese, with a body mass index (BMI) of 30 or greater.
  • If you have any history of heart disease, high blood pressure, or stroke, you should not take this combination. This is because phentermine and Wellbutrin can increase your heart rate and blood pressure, which could be dangerous for those with these conditions.
  • You also want to ensure to stay hydrated while taking this combination, as it can cause dehydration.
  • Finally, if you are pregnant or breastfeeding, you should not take this combination.

If you are ready to start your weight loss journey with phentermine and Wellbutrin, ensure to talk to your doctor first. They can help you determine if this combination is right for you and help you create a safe and effective plan.

With the proper precautions, you can lose weight with phentermine and Wellbutrin and improve your health.

Are Weight Loss Drugs Right for Me?

Weight loss drugs, such as phentermine and Wellbutrin, can help some people lose weight. But they’re not for everyone. If you’re considering taking these drugs, you must talk to your doctor about the potential risks and benefits.

You and your doctor can decide if weight loss drugs are right for you based on your medical history, how much weight you need to lose, other health concerns, and your response to previous attempts at weight loss.

If you have any of the following conditions, talk with your doctor before taking a weight-loss drug:

  • A history of drug or alcohol abuse
  • An eating disorder
  • Depression
  • Glaucoma
  • Heart disease or high blood pressure
  • Kidney disease
  • Seizures
  • Thyroid disease

You should also know that most weight loss drugs are not FDA-approved for children or teens under 18. If you’re considering a weight loss drug for your child, talk with the doctor first.

Is Wellbutrin an Appetite Suppressant?

No, Wellbutrin is not an appetite suppressant. It is an antidepressant that can sometimes help with weight loss, but it is not explicitly approved for this use.

suppressing appetite

What Antidepressant Works Well with Phentermine?

There is no definitive answer to this question, as each person responds differently to different medications. However, some people report weight loss when taking Phentermine in combination with Wellbutrin.

Conclusion

Phentermine and Wellbutrin are two medications you can use to help with weight loss. However, you must talk to your doctor before starting any new medicines, especially if you have a history of heart disease, high blood pressure, or stroke.

The safety of this combination is well-established, but you should still be aware of the potential side effects and take precautions to stay hydrated and avoid drug or alcohol abuse. With the right plan, you can lose weight safely with phentermine and Wellbutrin.

The Optima Healthy Gut Solution can also assist in your weight-loss journey. Get the Optima Healthy Gut Solution to help cleanse your body and lose weight.

It’s a critical vitamin that helps to break down essential nutrients and distribute them into your circulation.

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